Fetal Lung Maturation in Twin Gestations Based on Birth Order and Weight Discordance
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- FLM Index
研究概览
简要总结
Objectives:
To evaluate discordance in lung maturity in diamniotic twins based on birth order, sex and body weight. If we find discordance in fetal lung maturity in twin gestations this will change current practice of sampling only one amniotic sac for evaluation of fetal lung maturity.
详细描述
Objectives:
To evaluate discordance in lung maturity in diamniotic twins based on birth order, sex and body weight. If we find discordance in fetal lung maturity in twin gestations this will change current practice of sampling only one amniotic sac for evaluation of fetal lung maturity.
Hypotheses:
Lung maturation within twin pairs is weakly correlated based on presentation and estimated fetal weight.
Research Methods:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Diamniotic twin gestations
- •Twenty-four completed weeks gestation with dating calculated by their sure last menstrual period or utilizing a first trimester crown rump length ultrasound.
- •English Speaking
- •Scheduled cesarean section by patient's primary MD
排除标准
- •Monoamniotic twins
- •Presence of gross blood in amniotic sample
- •Presence of meconium amniotic fluid
- •Known/diagnosed fetal or newborn anomaly
- •Twin to Twin Transfusion Syndrome (TTTS)
- •Vaginal delivery
结局指标
主要结局
FLM Index
时间窗: 3 years
FLM Index
Lamellar Body Counts
时间窗: 3 years
Lamellar Body Counts
次要结局
- Respiratory Distress Syndrome(3 years)
- Transient Tachypnea in newborns(3 years)
- Neonatal Death(3 years)