Sensorimotor Treadmill Training to Improve Gait and Balance in Parkinson's Disease
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Parkinson's Disease
- Sponsor
- University of Erlangen-Nürnberg
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- Change from Baseline Gait Speed
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Persons with Morbus Parkinson commonly develop gait and balance disorders leading to dependence, loss of mobility and a high risk of falling.
This study investigates the effectiveness of a sensorimotor treadmill intervention to improve walking and balance abilities in persons with early stages of Parkinson's disease. The sensorimotor treadmill training is conducted on a special treadmill device which is challenging the participants by small oscillations. This intervention, which is supposed to simulate walking on natural, uneven surfaces, is compared to a conventional treadmill training.
Hypothesis: Sensorimotor treadmill training leads to larger improvements in walking and balance abilities as compared to conventional treadmill exercise.
Investigators
Prof. Dr. Klaus Pfeifer
Prof. Dr.
University of Erlangen-Nürnberg
Eligibility Criteria
Inclusion Criteria
- •Parkinson's disease stage 1-3 Hoehn and Yahr
- •United Parkinson Disease Rating Scale (UPDRS) 'gait' or 'postural stability' subscore of 1 or more
- •Ability to stand unaided and walk without an assistive device
- •Stable medication during the study period
Exclusion Criteria
- •On-off and wearing-off phenomena
- •Unstable medical or psychiatric illness
- •Clinically relevant cardiovascular or orthopaedic disease
- •Severe polyneuropathy
- •Cognitive impairment
Outcomes
Primary Outcomes
Change from Baseline Gait Speed
Time Frame: 8 weeks and 20 weeks
Self selected walking speed is assessed on a 10 meter walk distance
Change from Baseline Balance
Time Frame: 8 weeks and 20 weeks
Mini - Balance Evaluation Systems Test (Mini - BESTest), Postural Sway in the Romberg Test with eyes open and eyes closed for 30 seconds
Secondary Outcomes
- Change from Baseline Unified Parkinson's Disease Rating Scale (UPDRS)(8 weeks and 20 weeks)
- Change from Baseline Gait Performance(8 weeks and 20 weeks)
- Change from Baseline Mobility(8 weeks and 20 weeks)