跳至主要内容
临床试验/CTRI/2025/03/081738
CTRI/2025/03/081738尚未招募4 期

A COMPARATIVE ASSESSMENT OF THE CLINICAL OUTCOME IN TREATING GINGIVAL RECESSION USING CONNECTIVE TISSUE GRAFT WITH OR WITHOUT INJECTABLE T PRF ALONG WITH CORONALLY ADVANCED FLAP A SPLIT MOUTH STUDY

Seelam Praveen KUmar1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2025年3月20日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
15
试验地点
1
主要终点
Coverage of recession increase in width of attached gingiva

研究概览

简要总结

In this current split mouth study, a total number of 15 patients who will be visiting to the outpatient department of Periodontics will be selected for the present investigation through a careful selection process adhering to the inclusion and exclusion criteria, following the acquisition of informed consent. The quadrants will be categorized using flip coin method. The sites which will be treated with connective tissue graft alone will be considered as Group - I. Then sites which will be treated with connective tissue graft along with the injectable t-prf will be considered as Group - II.

·      Initially scaling and root planning will be done under local anesthesia followed by oral hygiene instructions. The patient will be recalled for periodontal surgery.

·      The following Clinical Parameters will be recorded at Baseline, one month, three months six months.

a.     Gingival bleeding index

b.     Plaque index

c.     Gingival recession depth

d.     Gingival recession width

e.     Clinical attachment level

f.      Keratinized tissue height

·       Connective tissue graft: We chose the harvesting site on the palate on the basis of the amount and quality of tissue and connective tissue graft was obtained by means of the De-epithelization of Free Gingival Graft.

·       Preparation t-prf: Intravenous blood was collected in two titanium tubes of 10ml without anticoagulant and centrifuged immediately at 700rpm for 3min at room temperature. The upper liquid layer was collected as injectable t-prf.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
All

入选标准

  • Systemically healthy patients with no history of periodontal therapy or use of antibiotics in the preceding 6 months that could affect the tissue response and remodeling.
  • Age group: 18-40 years Patients reported with similar bilateral or contralateral Millers Class 1 recessions at maxillary or mandibular incisors, canine with aesthetic compromise or dentinal hyper sensitivity.
  • Periodontal probing depths less than or equal to 2mm and areas of keratinized gingiva width greater than 2mm with no carious cervical lesions.
  • 3mm or more of recession depths.
  • Absence of restoration in the area to be treated.

排除标准

  • • Patients with known systemic disease • Patients with aggressive periodontitis • Use of tobacco in any form and alcoholism • Immunocompromised patients, pregnant or lactating females.

结局指标

主要结局

Coverage of recession increase in width of attached gingiva

时间窗: Base line, one month, three months, six months

次要结局

  • Increase in Gingival Phenotype(Base line, one month, three months, six months)

研究者

发起方
Seelam Praveen KUmar
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Seelam Praveen Kumar

Sree Sai Dental College And Research Institute

研究点 (1)

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