First Line Prevent Age Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy Aging
- Sponsor
- Prevent Age Resort "Pervaya Liniya"
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Reducing the degree of anxiety
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
To prove the effectiveness of complex wellness programs in terms of maintaining active longevity, including motivational counseling, high-intensity training, intermittent fasting, hypoxic training, as well as practices for achieving healthy sleep and mental well-being.
Clinical-instrumental, single-centre, prospective, open-label, non-randomized, sequential enrollment study with blinded endpoint analysis
Investigators
Anna Ratnikova
Cardiologist, MD, PhD, Chief physician, PervayaLiniyaResort, Russia
Saint Petersburg State University, Russia
Eligibility Criteria
Inclusion Criteria
- •Men and women over 18;
- •No significant (affecting the functional state) "active" diseases: acute diseases and exacerbations of chronic diseases;
- •Interest in active longevity and willingness to participate in research.
- •Signed informed consent.
Exclusion Criteria
- •Age up to 18 years;
- •Severe or moderate comorbidities;
- •Rheumatological (systemic / autoimmune) diseases of any severity;
- •Intestinal infections (within 3 months);
- •SARS / pneumonia, other diseases accompanied by systemic inflammation during the last 2 months;
- •Chronic inflammatory bowel disease;
- •Major surgery within the last 3 months
- •Intoxication (alcohol, drugs, other toxins);
- •Oncological disease (except for basalioma) out of remission;
- •Persons with mental illness;
Outcomes
Primary Outcomes
Reducing the degree of anxiety
Time Frame: First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit)
Reduction in the degree of anxiety according to the assessment of the Spielberger test
improved endothelial function
Time Frame: First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit)
improvement of flow-mediated vasodilatation measured by ultrasound (cuff test)
improved quality of night sleep
Time Frame: First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit)
improvement in nighttime sleep quality assessed by a Pittsburgh Sleep Quality Scale
Secondary Outcomes
- improved quality of night sleep(First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit))
- increased self-esteem(First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit))