Clinical Outcome and Urodynamic Changes of Tailored Transvaginal Mesh Surgery for Pelvic Organ Prolapse: a Mid-term Follow-up With a Median Duration of 30 Months
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lower Urinary Tract Symptoms
- Sponsor
- National Taiwan University Hospital
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- Voiding difficulty
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Lower urinary tract symptoms may change after pelvic organ prolapse surgery. Thus, the aim of this study was to elucidate (1) the changes of lower urinary tract symptoms and (2) the changes in values of urodynamic parameters between baseline and after pelvic organ prolapse surgery.
Detailed Description
Between November 2011 and December 2015, medical records of all consecutive women who underwent anterior transvaginal mesh surgery (ATVM) but without concomitant mid-urethral sling surgery were reviewed. Data of pre- and post-operative lower urinary tract symptoms and urodynamic parameters were compared. The bladder outlet obstruction was defined when the detrusor pressure at maximum flow rate was not less than 40cmH2O, and the maximum flow rate was less than 12 mL/s. Overactive bladder syndrome, detrusor overactivity, bladder oversensitivity and urodynamic stress incontinence were also recognized as international continence society definition. STATA software was used for statistical analysis. Wilcoxon signed-rank test or McNemar's test was used for statistical analysis as appropriate. P \< 0.05 was considered as statistically significant.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Women with pelvic organ prolapse
- •Women received anterior transvaginal mesh surgery
Exclusion Criteria
- •Concomitant mid-urethral sling surgery
- •Chronic urinary tract infection
- •Interstitial cystitis
- •Malignancy history in pelvic organ
- •Ever received pelvic radiation
- •Concomitant transabdominal surgery
Outcomes
Primary Outcomes
Voiding difficulty
Time Frame: November 2011 to December 2015
Weak stream of urination, intermittency, strain to void or incomplete empty sensation after the anterior transvaginal mesh surgery
Secondary Outcomes
- Overactive bladder syndrome(November 2011 to December 2015)