EUCTR2005-001004-39-GB进行中（未招募）1 期
Investigation of combined phosphodiesterase 5 inhibitor and isosorbide mononitrate for the treatment ofresistant hypertension - Sildenafil and isosorbide mononitrate in resistant hypertension
niversity of Edinburgh0 个研究点目标入组 40 人开始时间: 2005年5月6日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •?Essential hypertension
- •?Office BP >140/85 despite treatment with 3 or more antihypertensive agents
- •?Resistance to treatment proven by directly observed therapy
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •?Identifiable underlying cause for hypertension (e.g. Conn’s or Cushing’s syndromes, renal artery stenosis, phaeochromocytoma, coarctation of the aorta)
- •?Clinically evident coronary artery or cerebrovascular disease
- •?Taking regular organic nitrates or nicorandil
- •?Significant renal or liver impairment
- •?Current alcohol or drug abuse
- •?Previous serious drug allergy
研究者
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