Neuromuscular Electrical Stimulation Improves Exercise Tolerance in Patients With Advanced Heart Failure on Continuous Dobutamine Use - A Randomized Controlled Trial

Federal University of São Paulo1 site in 1 country49 target enrollmentJanuary 2010

ConditionsHeart Failure Ventricular Dysfunction, Left

Overview

Phase: N/A
Intervention: Not specified
Conditions: Heart Failure
Sponsor: Federal University of São Paulo
Enrollment: 49
Locations: 1
Primary Endpoint: Functional capacity evaluated using the 6-minute walk test (6MWT)
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether neuromuscular electrical stimulation can improve exercise tolerance for patients with heart failure and continuous dobutamine use in a hospital.

Registry

clinicaltrials.gov

Start Date

January 2010

End Date

December 2014

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Federal University of São Paulo

Responsible Party

Principal Investigator

Patricia Forstieri

Federal University of São Paulo

Eligibility Criteria

Inclusion Criteria

•Advanced heart failure (Stage D - Left ventricle ejection fraction \<30%)
•New York Heart Association class III-IV
•Standard medical therapy for heart failure management
•Continuous inotropic infusion

Exclusion Criteria

•Unstable angina pectoris
•Recent (6 months) acute coronary syndrome
•Arrythmias
•Chronic renal failure
•Diabetes Mellitus
•Peripheral vascular diseases
•Inability to walk

Outcomes

Primary Outcomes

Functional capacity evaluated using the 6-minute walk test (6MWT)

Time Frame: Change from assessment at admission and at patient discharge

Functional capacity was evaluated using the 6-minute walk test (6MWT), by a single evaluator blinded to the group allotment, in accordance with American Thoracic Society criteria.