Tear Film Studies In Children With Vernal Keratoconjunctivitis

Not Applicable

Conditions: Health Condition 1: H162- Keratoconjunctivitis

Registration Number: CTRI/2022/01/039611

Lead Sponsor: Department of Ophthalmology

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1. CASES: Patients with vernal keratoconjunctivitis on no treatment or only on mast cell stabilisers

Children of 4 to 18 years of age presenting to the OPD with moderate to severe ocular discomfort (itching, photophobia, foreign body sensation, discharge, burning), papillae on upper tarsal conjunctiva or Horner Tranta dots on the limbus.

2. CONTROLS: Children of 4 to 18 years of age attending the OPD for refraction tests with no ocular surface problems.

Exclusion Criteria

1. Patients of vernal keratoconjunctivitis on treatment with steroids or lubricant drops

2. Vernal keratoconjunctivitis with accompanying shield ulcer

3. Ocular diseases like blepharitis, active ocular infections, lid abnormalities

4. Chemical, thermal or radiation injury to eye

5. Systemic diseases (other than atopy)

6. History of Steven Johnson syndrome

7. Previous ophthalmic surgery

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measurement of parameters related to tear film stability. <br/ ><br>â?¢ Schirmer test <br/ ><br>â?¢ Tear film break up time <br/ ><br>â?¢ Lissamine green stain <br/ ><br>â?¢ Meibomian gland drop-out <br/ ><br>Timepoint: at baseline

Secondary Outcome Measures