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临床试验/CTRI/2026/02/104725
CTRI/2026/02/104725尚未招募2/3 期

A randomised comparative clinical study to evaluate the efficacy of virechana karma and ksheeradhara in raktagatavata w.s.r hypertension with sarpagandha churna as shamana aushadhi.

Institute of Post Graduate Ayurvedic Education and Research at SVSP Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年3月15日最近更新:
适应症
相关药物

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
1 to reduce Systolic blood pressure from 159 mm of hg to 140 mm of hg

研究概览

简要总结

Hypertension is most common lifestyle disorder, It is chronic and often asymptomatic medical condition where BP elevated beyond normal limit.Various Ayurvedic scholar coined different name of Hypertension,Here Raktagatavata is corelated with Hypertension. Hypertension is directly responsible for 57% of all stroke deaths and 24% of all coronary heart dis-ease (CHD) deaths in India. It is the most potent risk factor for diseases of the brain, kidney, heart and peripheral arteries which may prove fatal if not man-aged effectively. Hypertension is a silent killer be-cause most sufferers (85%) are asymptomatic. In 95% of the cases of hypertension, the exact underlying cause is still unknown but is believed to be due to genetic and environmental factors. Hypertension can-not be considered as a Vyadhi (Disease) as per Ayurveda, but it can be understood by assessing the in-volved Doshas, Dooshyas (Entity which is affected by morbid Dosha), Srotas etc. Many Ayurvedic scholars have proposed different theories about how hypertension can be understood in Ayurveda, but there is no standardized and widely accepted view about the Ayurvedic pathogenesis of this condition. Thus, an attempt is made to understand the Samprapti of various types of hypertensions and to find an ideal Chikitsa Sutra ( treatment protocol)2-4 for the management of Raktagatavata.In this Study virechana and ksheeradhara has been applied along with Sarpagandha churna in Raktagatava. In modern medicine there are lots of Complication like, Pedal oedema, left ventricular hypcotrophy, So in Ayurvedic Medicine and therapy there is long lasting effect of over the disease hypertension and no side effects. This is a single centred two arm parallel group with blinded outcome,randomized control trial .Total 60 patient with (30-65) years of age irrespectively of sex , Primary Hypertension (Systolic 140-159 mm of Hg and Diastolic 90- 99 mm of Hg) will be divided into two groups.One on Virechana karma by Trivit Lehyam along with powder sarpagandha, second one ksheeradhara along with powder sarpagandha will be given to the participants.person will be selected strictly on the basis of inclusion and exclusion criteria for this trial programme.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
35.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • •Irrespective of sex, race and religion Systole Blood Pressure within 140-159 mm of Hg Diastolic Blood Pressure within 90 to 99 mm Hg Participants are not taking any hypertensive anti lipidemic medication for 3 months prior to enrollment.

排除标准

  • •Patients with cardiac failure, congenital heart diseases, renal failure Prehypertensive with uncontrolled diabetes Abuse of alcohol and drugs Pregnant mother.

结局指标

主要结局

1 to reduce Systolic blood pressure from 159 mm of hg to 140 mm of hg

时间窗: 45 days

to reduce diastolic blood pressure from 99 of hg to 90 mm of Hg

时间窗: 45 days

次要结局

  • to observed the symptoms of pain(any abnormal body temperature)

研究者

发起方
Institute of Post Graduate Ayurvedic Education and Research at SVSP Hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Sayantan Bera

Institute of Post Graduate Ayurvedic Education and Research at SVSP Hospital

研究点 (1)

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