Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Bahria University
- Enrollment
- 46
- Locations
- 1
- Primary Endpoint
- Glycated Hemoglobin
Study Overview
Brief Summary
The goal of this clinical trial is to compare efficacy and safety of metformin versus apple cider vinegar in prediabetics . The main question[s] it aims to answer are:
- Efficacy of metformin versus apple cider vinegar in prediabetics
- Safety of metformin versus apple cider vinegar in prediabetics
Researchers will compare group of prediabetics taking metformin with group of prediabetics taking apple cider vinegar to see if there is difference in safety and efficacy..
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 17 Years to 40 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Males and Female
- •17-40 years age
- •Body Mass index (BMI) overweight and obese
- •FBS (100-125 mg/dl)
- •HBA1c 5.7% to 6.4%
Exclusion Criteria
- •Concomitant medical problems as established diabetes, hepatic or renal insufficiencies etc.
- •Known allergy or intolerance to metformin or apple cider vinegar
Arms & Interventions
Apple cider vinegar
Apple Cider Vinegar 15ml per day diluted in 200 ml of water for 12 weeks
Intervention: Apple cider vinegar (Dietary Supplement)
Metformin
Tablet Metformin HCl 500 mg per oral twice daily for 12 weeks
Intervention: Metformin Hydrochloride (HCL) (Drug)
Outcomes
Primary Outcomes
Glycated Hemoglobin
Time Frame: 12 weeks
Change in glycosylated hemoglobin (HbA1c ) in percent
Fasting Blood Sugar
Time Frame: 12 weeks
Change in fasting blood sugar (FBS) in mg/dL
Secondary Outcomes
No secondary outcomes reported
Investigators
Dr. Shizma Junejo
Senior Lecturer Pharmacology Department
Bahria University