Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- Glycated Hemoglobin
研究概览
简要总结
The goal of this clinical trial is to compare efficacy and safety of metformin versus apple cider vinegar in prediabetics . The main question[s] it aims to answer are:
- Efficacy of metformin versus apple cider vinegar in prediabetics
- Safety of metformin versus apple cider vinegar in prediabetics
Researchers will compare group of prediabetics taking metformin with group of prediabetics taking apple cider vinegar to see if there is difference in safety and efficacy..
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 17 Years 至 40 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Males and Female
- •17-40 years age
- •Body Mass index (BMI) overweight and obese
- •FBS (100-125 mg/dl)
- •HBA1c 5.7% to 6.4%
排除标准
- •Concomitant medical problems as established diabetes, hepatic or renal insufficiencies etc.
- •Known allergy or intolerance to metformin or apple cider vinegar
研究组 & 干预措施
Metformin
Tablet Metformin HCl 500 mg per oral twice daily for 12 weeks
干预措施: Metformin Hydrochloride (HCL) (Drug)
Apple cider vinegar
Apple Cider Vinegar 15ml per day diluted in 200 ml of water for 12 weeks
干预措施: Apple cider vinegar (Dietary Supplement)
结局指标
主要结局
Glycated Hemoglobin
时间窗: 12 weeks
Change in glycosylated hemoglobin (HbA1c ) in percent
Fasting Blood Sugar
时间窗: 12 weeks
Change in fasting blood sugar (FBS) in mg/dL
次要结局
未报告次要终点
研究者
Dr. Shizma Junejo
Senior Lecturer Pharmacology Department
Bahria University