跳至主要内容
临床试验/CTRI/2025/06/089039
CTRI/2025/06/089039尚未招募2 期

An Open Labelled Randomized Controlled Clinical Study to Evaluate The Efficacy of Devdarvyadi Churna and Vyaghri Churna in Management of Kaphaja Kasa W.S.R. to Chronic Bronchitis.

Parul Institute of Ayurved1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年1月7日最近更新:
适应症

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
To assess the Anti-inflammatory and expectorant effect of Devdarvyadi Churna in comparison with Vyaghri Churna in the management of Kaphaja Kasa on the basis of ESR, AEC.

研究概览

简要总结

In recent years, there has been a notable rise in respiratory diseases. According to the National Center for Health Statistics, 62 million cases of common cold and cough occur annually, and cough ranks as the fifth most common symptom for which medical care is sought. Chronic bronchitis affects about 9.5 million people, primarily those over 50 years old. In Ayurveda, Kasa (cough) is described as a disease, symptom, or complication. Kaphaja Kasa, a type of Ardra Kasa, is dominated by Kapha and Vata involvement and is comparable to chronic bronchitis due to similarities in symptoms like persistent productive cough. Chronic bronchitis involves inflammation of bronchi with sputum production for at least three months over two consecutive years and is linked to pollutants, smoking, and infections. If untreated, Kasa can lead to serious conditions like Shwasa (asthma) or Rajyakshma (tuberculosis). The Devdarvyadi Churna, mentioned by Acharya Charaka, contains herbs like Devdaru, Haritaki, Musta, and Pippali along with Madhu (honey), which help in pacifying Kapha and regulating Vata. With Ushna Veerya, Deepana, and Pachana properties, this formulation aids in digestion and relieves cough. Hence, this study aims to evaluate its efficacy in managing Kaphaja Kasa.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
30.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • •Chronicity From 3 months to 2 Consecutive Years Patients having symptoms of Chronic Bronchitis copious and purulent sputum and frequent episodes of respiratory insufficiency Patient willing to sign the informed consent and can participate in the study procedure Patients having FEV1 between 50% to 80%.

排除标准

  • •Pregnant or lactating women.
  • •Immunocompromised status such as HIV, Tuberculosis, Cancer etc.
  • •History of upper or lower respiratory tract infection, within the previous 30 days.
  • •Subjects suffering from Acute Bronchitis.
  • •K/C/O pneumonia, plural effusion, pneumothorax, heart disease, secondary severe infection.
  • •Patients with uncontrolled Hypertension and uncontrolled Diabetes.

结局指标

主要结局

To assess the Anti-inflammatory and expectorant effect of Devdarvyadi Churna in comparison with Vyaghri Churna in the management of Kaphaja Kasa on the basis of ESR, AEC.

时间窗: 2 Months

次要结局

  • To assess the Anti-inflammatory & expectorant effect of Devdarvyadi Churna in comparison with Vyaghri Churna in the management of Kaphaja Kasa on the basis of Spirometry, SGRQ.(2 Months)

研究者

发起方
Parul Institute of Ayurved
申办方类型
Private medical college

研究点 (1)

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