Impact of Ascending Aorta Replacement by Graft on Elastic Properties of Descending Thoracic Aorta Evaluated by Cardiac Magnetic Resonance Imaging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 19
- 主要终点
- Aortic compliance of descending aorta (mm2/mmHg)
研究概览
简要总结
The aim of our study was to evaluate the impact of aortic root replacement by a graft on the elastic properties of the descending thoracic aorta using cardiac Magnetic Resonance Imaging (MRI) and automatic post-processing.
Nineteen patients were operated on an aortic root aneurysm and a cardiac MRI allowing aortic compliance measurement was performed before and after surgery. Images were acquired with a 1.5 T MRI with only one additional sequence to a conventional aortic MRI protocol.
详细描述
Observational and retrospective trial on medical data only. The patients are operated of planned aortic root aneurysm without additional intervention.
The pre and postoperative cardiac MRI are planned in standard of care.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •> 18 years
- •Elective patient
- •Ascending aorta replacement with graft
排除标准
- •Prior cardiac surgery
- •Contraindication to performing cardiac MRI
结局指标
主要结局
Aortic compliance of descending aorta (mm2/mmHg)
时间窗: post-operative cardiac MRI performing between 12 and 24 months
Aortic elastic properties of the descending aorta before and after aortic root replacement using cardiac MRI. Aortic compliance is a local measurement of elastic properties which is obtained with cardiac MRI images by computer processing.
次要结局
- Aortic compliance of ascending aorta (mm2/mmHg)(post-operative cardiac MRI performing between 12 and 24 months)
研究者
MORGANT Marie-Catherine
PI
Centre Hospitalier La Chartreuse