Effects of Interactive Stepping Exercise on Balance and Cognitive Function in Individuals With Parkinson's Disease
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Romberg test
Study Overview
Brief Summary
The objective of this study is to investigate the effects of interactive stepping exercise on balance and cognitive function in individuals with PD.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 50 Years to 85 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Idiopathic PD
- •Hoehn & Yahr stage between 1 to 3
- •Age between 50 to 85
- •Stable pharmacologic treatment for the last 2 weeks
- •Ability to walk 10 meters unassisted or with assistive devices
Exclusion Criteria
- •Other neurological disorders diagnosis than PD
- •Receiving any neurological surgeries
- •Any musculoskeletal disorder or cardiopulmonary disease that may influence participation in the study
- •The Mini-Mental State Examination (MMSE) < 24 scores
- •Participated in other exercise intervention of study in the past 3 months
- •Colorblindness or color vision deficiency
Arms & Interventions
Interactive stepping exercise group
Participants will execute interactive stepping exercise 2 times per week for 8 weeks (16 sessions).
Intervention: Interactive stepping exercise (Other)
Square stepping exercise group
Participants will execute square stepping exercise 2 times per week for 8 weeks (16 sessions).
Intervention: Square stepping exercise (Other)
Outcomes
Primary Outcomes
Romberg test
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate static balance ability
Sharpened Romberg test
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate static balance ability
One-leg stance test
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate static balance ability
Timed up and go test
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate functional walking ability
Mini-Balance Evaluation Systems Test
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate balance ability
Montreal Cognitive Assessment Chinese version
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate global cognitive function
Digit span test
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate executive function
Stroop color and word test Chinese version
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate executive function
Trail-making test Chinese version
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate executive function
Spatial span test
Time Frame: Change from baseline at 8 weeks and 12 weeks
To evaluate visuospatial ability
Secondary Outcomes
- 10-meter walk test(Change from baseline at 8 weeks and 12 weeks)
- Parkinson's Disease Questionnaire 39(Change from baseline at 8 weeks and 12 weeks)
Investigators
Yea-Ru Yang
Professor
National Yang Ming Chiao Tung University