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Clinical Trials/NCT04574479
NCT04574479
Completed
Phase 4

Impact of Supra-inguinal Fascia Iliaca Compartment Block on Postoperative Opioid Consumption in Total Hip Arthroplasty Interventions by Posterior Approach

University of Liege1 site in 1 country86 target enrollmentDecember 16, 2020

Overview

Phase
Phase 4
Intervention
Multimodal analgesia and PCA morphine pump
Conditions
Arthropathy of Hip
Sponsor
University of Liege
Enrollment
86
Locations
1
Primary Endpoint
Opioid sparing
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Find the impact of supra-inguinal fascia iliaca compartment block on postoperative pain management after total hip arthroplasty by posterior surgical approach

Detailed Description

ASA physical status 1, 2 and 3 patients scheduled to undergo elective surgery of total hip arthroplasty under spinal anesthesia. The investigators would like to study the impact of supra-inguinal fascia iliaca block on postoperative pain management after total hip arthroplasty by posterior surgical approach. The principal investigator perform this block with ultrasound technique. The investigators also want to observe if this loco-regional new approach to fascia iliaca block could have influence on opioid side effects, postoperative nausea and vomiting, length of hospitalisation and first mobilisation side effects.

Registry
clinicaltrials.gov
Start Date
December 16, 2020
End Date
September 2, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jean François Brichant

Head of Anesthesiology Department

University of Liege

Eligibility Criteria

Inclusion Criteria

  • Adults patients scheduled to undergo elective surgery of total hip arthroplasty by posterior surgical aboard

Exclusion Criteria

  • Patient refusal
  • Allergy to used medications or local infection.
  • Pregnancy
  • Obesity with body mass index \> 35
  • History of chronic pain or fibromyalgia
  • Drug (opioids) addiction
  • Treatment with corticosteroids for more than 6 months
  • Severe kidney or liver diseases
  • Mental disorders or serious neurological diseases

Arms & Interventions

Placebo

Placebo group: patients have multimodal analgesia without fascia-iliaca compartment block

Intervention: Multimodal analgesia and PCA morphine pump

Fascia iliaca block

Patients in this arm have multimodal analgesia with supra-inguinal fascia iliaca compartment block before surgery

Intervention: Supra-inguinal fascia iliaca compartment block

Fascia iliaca block

Patients in this arm have multimodal analgesia with supra-inguinal fascia iliaca compartment block before surgery

Intervention: Multimodal analgesia and PCA morphine pump

Outcomes

Primary Outcomes

Opioid sparing

Time Frame: 48 hours after the intervention

Difference in cumulated morphine consumption in the first 48 hours after surgery

Secondary Outcomes

  • Opioid secondaries effects(48 hours after the intervention)
  • Pain management satisfaction: questionnaire(48 hours after the intervention)

Study Sites (1)

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