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临床试验/CTRI/2017/11/010546
CTRI/2017/11/010546招募中4 期

Comparison of efficacy and evaluation of the optimal flow rate for desflurane anaesthesia at three different settings

Dr L H Hiranandani Hospital1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2015年1月7日最近更新:

试验速览

阶段
4 期
状态
招募中
入组人数
150
试验地点
1
主要终点
Efficacy of desflurane with respect to maintenance haemodynamic parameters and depth of anaesthesia

研究概览

简要总结

This study is conducted to evaluate the optimal flow rate for using desflurane at low flows, its efficay for maintenance of depth of anaesthesia and haemodynamic stability. We would like to evaluate that by decreasing the flow rates does the consumption of desflurane actually reduces. We would also like to highlight the safety of oxygenation with low flow rates and the recovery out come of the patient post stopping desflurane.

研究设计

研究类型
Interventional
分配方式
Random Number Table
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • ASA 1 and 2 patients undergoing General anaesthesia for laprascopic abdominal and pelvic surgeries
  • Surgeries lasting approximately 30 minutes to 180 minutes
  • Patients giving valid consent
  • Age:18 to 70 year.

排除标准

  • •Patient refusal •ASA grade >2 •Chronic alcoholics/ smokers, acute alcohol intoxication •Pregnant women •Patients with neuromuscular diseases •Suspected Malignant hyperthermia •Persons with epidural analgesia catheter.

结局指标

主要结局

Efficacy of desflurane with respect to maintenance haemodynamic parameters and depth of anaesthesia

时间窗: At all time points intraoperatively after starting desflurane to switching off desflurane

次要结局

  • 1. Safety of low flow rates assessed by oxygenation of the patient(2. Incidence of awareness under anaesthesia)

研究者

申办方类型
Research institution and hospital

研究点 (1)

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