Spinal Motor Evoked Potentials During Neurosurgical Procedures Within the Central Region
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Clinical motor status according to the MRC scheme
研究概览
简要总结
During neurosurgical resection of brain tumors within brain areas for motor control, it is important to monitor motor function. For this muscle motor evoked potentials are used. Those are elicited by transcranial and direct cortical stimulation. Motor responses are recorded from muscles. In neurosurgical procedures for spinal cord tumors, the same methods are used, but additionally motor activity is recorded from the spinal cord. This is called spinal motor evoked potentials. It is known that the relation between spinal and muscle motor evoked potentials helps to extent the resection of spinal cord tumors. This study implements the spinal motor evoked potential into brain tumor surgery and analyses the relationship between spinal and muscle motor evoked potentials. With this, detection of injury to the brain area for motor control might be discovered earlier and thus tumor resection can be performed safely.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •> 18 years
- •tumor location adjacent to the motor cortex and corticospinal tract
排除标准
- •neurological degenerative diseases
- •neurological immunological diseases
- •drug abuse
- •implanted medical devices such as cardiac pacemaker
- •spine deformation
结局指标
主要结局
Clinical motor status according to the MRC scheme
时间窗: 6 months
clinical motor status according to the MRC scheme
D-wave measurement
时间窗: 24 hours
numeric assessment, amplitude and latency of D-wave
次要结局
未报告次要终点
研究者
Andrea Szelenyi
Professor
Heinrich-Heine University, Duesseldorf
