Impact of a Chronic Disease Management Model in patients with decompensated liver disease: The Australian Liver Failure Trial (ALFIE)

Not Applicable

Completed

• Conditions: Decompensated Liver Disease; Liver Cirrhosis; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12617001293358
• Lead Sponsor: Southern Adelaide Local Health Network

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-09-07
• Study Completion: 2022-05-06
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 147

Inclusion Criteria

Cirrhosis of the liver
Current admission with an episode of decompensation including ascites, encephalopathy, variceal bleed, SBP, or HRS OR Admission within last 6 months with decompensation episode as above and is currently Childs Pugh score B or C.
Able to comprehend and sign an informed consent form (West Haven Criteria 0-1)
Age > 18

Exclusion Criteria

Active HCC
Involvement in a multidisciplinary heart failure program
Active management by Palliative care services or expected survival of <3 months
Currently on the liver transplant waiting list

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Emergency liver-related hospital admission rates - patient case notes and hospital databases will be searched to record emergency attendances and admissions and whether they were Liver-related and how many days were spent in ICCU.[ Admissions will be collected at 12 months and at the end of the trial (24 months post trial commencement date/recruitment start).]