JPRN-jRCTs051180180已完成4 期
Prospective randomized trial to compare two treatment regimens of rituximab for adult refractory nephrotic syndrome - OPTIMALNS
Hayashi Terumasa0 个研究点目标入组 64 人开始时间: 2019年3月26日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 64
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 ot applicable(—)
- 性别
- All
入选标准
- •1) Patients who have developed nephrotic syndrome at age less than 18 years old and have been dependent to steroid alone or a combination with calcineurin inhibitors.
- •2) Patients who have developed nephrotic syndrome at 18 years old or older and have been dependent or resistant to steroid alone or a combination with calcineurin inhibitors and have been complicated with adverse effects of these drugs (e.g., diabetes, morbid fracture).
- •3) Patients diagnosed by renal biopsy as having minimal change disease or focal segmental glomerulosclerosis.
- •4) Patients who are at least 20 years old when they give informed consent.
排除标准
- •1) Patients diagnosed by renal biopsy as having any pathology other than minimal change disease or focal segmental glomerulosclerosis.
- •2) Patients with malignant disease or hematological disease.
- •3) Patients who are or may be pregnant, breast-feeding or hope to be pregnant during the study period.
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