Comparison of fractional co2 laser therapy alone and with its combination with topical timolol or topical insulin in the treatment of acne scar

Phase 3

Recruiting

• Conditions: Acne scar.; Scar conditions and fibrosis of skin; L90.5

• Registration Number: IRCT20150825023753N23
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

The patients with moderate to severe atrophic acne scarring and no inflammatory lesions
Age above 15 years old

Exclusion Criteria

Pregnant and lactating patients
Patients who have inflammatory lesions
Patients who have active Koebner-inducing diseases such as psoriasis and Lichen planus
Patients who have Asthma, atrioventricular blocks, sinus bradycardia, diabetes mellitus
Prior use of beta blockers,
The patients who have received Isotretinoin in the past three months.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of acne scar. Timepoint: At the beginning of the study and after two months. Method of measurement: Scale for Acne Scar Severity (SCAR-S),.;Acne Scar Assessment Scale. Timepoint: At the beginning of the study and after two months. Method of measurement: Acne Scar Assessment Scale (ASAS).;Grading of scar. Timepoint: At the beginning of the study and after two months. Method of measurement: Goodman and Baron quantitative global scarring grading system (GBAQGS).

Secondary Outcome Measures

Name	Time	Method
Dermatologic Life Quality Index. Timepoint: At the beginning of the study and after two months. Method of measurement: Dermatologic Life Quality Index (DLQI) questionnaire.