ISRCTN18062761已完成不适用
Efficacy of ascorbic acid and/ N-Acetylcysteine (NAC) supplementation on nutritional, antioxidant status, and respiratory function of male Chronic Obstructive Pulmonary Disease (COPD) patients: a randomized controlled trial
ational University of Malaysia (Universiti Kebangsaan Malaysia) (Malaysia)0 个研究点目标入组 79 人开始时间: 2012年1月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 79
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Male
入选标准
- •1. An established clinical history of COPD diagnosed by the physician, with pre-bronchodilator forced expiratory volume in 1 second (FEV1) % predicted 30?80%, which was defined as stage I, II and III based on the American Thoracic Society (2004) definition.
- •2. Patients aged between 35 to 75 years old who did not take any antioxidant supplementation for the past three months, not diagnosed with co-morbidities such as diabetes mellitus (DM), tuberculosis (TB), and inflammatory disease, and had not been hospitalized for the past three months prior to the study
排除标准
- •1. Patients with co-morbidities such as diabetes mellitus (DM), tuberculosis (TB) and inflammatory disease and taking about 500 mg vitamin C through their diet or vitamin C supplements
- •2. The patients who took drugs such as aspirin, estrogen, amphetamine and cholesyramine regularly for the past three months which affected absorption of vitamin C
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