Para-Vertebral Dexmedetomidine in Video-Assisted Thoracic Surgeries for Acute and Chronic Pain Prevention; A Randomized Double Blinded Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- acute postoperative pain
研究概览
简要总结
Up to our knowledge there is no study focused upon the incidence of post VATS chronic pain when dexmedetomidine is used.
详细描述
Most Video-Assisted Throcoscopy Surgery (VATS) procedures are considered low-risk interventions requiring short hospital stays or even outpatient settings. Because of these factors, VATS did not raise as much interest as thoracotomy in its postoperative pain management. However, it is a fact that pain following VATS can be severe and long-lasting .According to Richardson and colleagues, 38% of VATS procedures present persistent pain two months after surgery as a result of acute nerve damage during the surgical procedure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA II-III
- •Video-assisted thoracic surgery
排除标准
- •Patient refusal
- •Allergy to medication
- •Coagulopathy
- •Malformation
研究组 & 干预措施
Dexmedetomidine
Dexmedetomidine is added to bupivacaine the paravertebral block
干预措施: Dexmedetomidine (Drug)
Bupivacaine
Bupivacaine only in the paravertebral block
干预措施: Bupivacaine (Drug)
结局指标
主要结局
acute postoperative pain
时间窗: 24 hours
assessment of pain by visual analog scale (VAS) by cm with minimal =0 and maximal =10, worst pain mean scale of 10
次要结局
- chronic post thoracic surgery pain(3 months)
研究者
Emad Zarief , MD
Associate professor
Assiut University