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Treatment of edge-stenosis in endografts, inserted for occlusive disease in the femoral superficial artery (SFA), with Drug Eluting Balloons (DEB).

Completed
Conditions
Stenosis and atherosclerosis in the endograft in the SFA
10003184
10003216
Registration Number
NL-OMON39003
Lead Sponsor
Rijnstate Ziekenhuis
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
23
Inclusion Criteria

Patients over 18 years of age
Signed informed consent
Edge stenosis of the endograft in the SFA with a peak systolic velocity ratio (PSV ratio) of >2.5
Target vessel diameter > or equal to 4 mm and < or equal to 7 mm

Exclusion Criteria

-Pregnancy or breast feeding women
-Known allergies or sensitivity to heparin, aspirin, other anticoagulant/antiplatelet therapies, -paclitaxel or contrast media that cannot be adequately pre-treated prior to index procedure
-Patient unsuitable for administration of contrast agent
-Stroke or heart attack within 3 months prior to enrollment
-Enrolled in another investigational drug, device or biologic study
-Any surgical procedure or intervention performed within 30 days prior to or post index procedure
-Failure to successfully cross the target lesion
-Angiographic evidence of severe calcification
-Dementia or altered mental status that would prohibit giving conscious informed consent
-Need for adjunctive major surgical or vascular procedures within one month
-Untreated flow-limiting aortoiliac occlusive disease
-Severe medical comorbidities (untreated CAD/CHF, severe COPD, metastatic malignancies, dementia etc.) or other medical condition that would preclude compliance with study protocol
-Any previously known coagulation disorder, including hypercoagulability

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Patency rates after treatment with DEB (after 30-days and after 1 year) </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Complications </p><br>
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