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临床试验/NCT04877886
NCT04877886Unknown不适用

A Novel Technique for the Assessment of Non-traumatic Pain Diagnosis in the Emergency Department.

Taipei City Hospital2 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2021年6月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
120
试验地点
2
主要终点
The diagnostic rate of ultrasound with IV contrast in acute flank pain patient

研究概览

简要总结

To evaluate the efficiency of ultrasound with IV contrast and compare this with the Computed Tomography in acute flank pain patient at Emergency Department.

详细描述

Acute flank pain is a common chief complaint in emergency departments (ED), but it is a challenge for physicians in ED to accurately diagnose. It can cause variable diseases and is in many cases lethal (e.g. aortic dissection, ruptured aortic aneurysm, renal artery dissection, ruptured tumor, etc). The computed tomography scan with IV contrast is an ideal tool to diagnose due to its high sensitivity and specificity and is a golden standard examination. However, currently point-of-care ultrasound is routinely used as first-line technique. As this procedure is non-invasive and has no radiative effect, it is considered more logical, especially for those critical patients who are not able to move and perform the CT scan. Furthermore, the iodine contrast of CT scan is known as renal toxicity and should be used with caution in patient with hyperthyroidism and allergy to the contrast. The radiation of CT scan would be harmful to the pregnant patient as well.

IV contrast ultrasound is a novel technique nowadays and it is widely used in diagnosing breast, liver, renal and pancreatic tumors. The ultrasound contrast using air microbubbles could enhance the scanning quality and also has high sensitivity and specificity. In ED, ultrasound with contrast now could be applied to the abdominal trauma and pediatric injury. For those patients with poor renal function, thyroid disease and pregnant women who cannot undergo IV contrast CT, IV contrast ultrasound provides a faster and safer way to evaluate patients in ED. We compared CT and ultrasound with IV contrast to determine the difference in efficiency between both examinations.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Diagnostic
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Acute flank pain who visit ER

排除标准

  • Younger than 18 years old
  • Known allergy to contrast

结局指标

主要结局

The diagnostic rate of ultrasound with IV contrast in acute flank pain patient

时间窗: The hospitalization of each participant, up to 28 days

Evaluate the sensitivity and specificity in ultrasound scan

次要结局

  • To compare the efficiency over the ultrasound and CT scan within or without contrast(The hospitalization of each participant, up to 28 days)

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Hung,Tzu-Yao

Emergency Medicine Physician

Taipei City Hospital

研究点 (2)

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