Prevention effect of low dose proton pump inhibitor for nonvariceal upper gastrointestinal bleeding in Chronic kidney disease in patients taking aspirin.
Not Applicable
Completed
- Conditions
- Diseases of The genitoruinary system
- Registration Number
- KCT0000814
- Lead Sponsor
- Hallym University Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
1. chronic kidney disease stage with eGFR < 60 ml/min/1.73m2 or end stage renal disease
2. the patients taking low dose aspirin (325mg or less per day)
Exclusion Criteria
1. Concomitant use of H2 receptor blocker, anticoagulant agents or corticosteroids
2. A history of peptic ulcer disease, gastric surgery, chronic liver disease
3. A history of malignancy including stomach
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method hematemesis, melena, hematochezia, hemoglobin
- Secondary Outcome Measures
Name Time Method Systolic blood pressure;packed red blood cells;endoscopic finnding,;endoscopioc bleeding control procedure;operation;mortality