Investigating predictors of the antidepressant efficacy of Transcranial Magnetic Stimulation

Professor Paul Fitzgerald0 个研究点目标入组 120 人开始时间: 2010年12月6日最近更新: 2020年1月13日

试验速览

暂无简介。

•Have a DSM-IV diagnosis of a Major Depressive Episode (SCID II).
•Are aged 18-75.
•Have treatment resistant depression at Stage III of the Thase and Rush classification (27).
•Have a Hamilton Depression Rating Scale (HAMD) score of > 20 (moderate to severe depression).
•Have had no increase or initiation of new antidepressant (or other psychoactive) therapy in the 4 weeks prior to screening

•Have an unstable medical condition, neurological disorder, any history of a seizure disorder, or are currently pregnant or lactating.
•In the opinion of the investigator, are at sufficient risk of suicide to require immediate electroconvulsive therapy.
•Have a current DSM-IV diagnosis of Substance Abuse or Dependence disorder, a diagnosis of a personality disorder (SCID II) or another Axis 1 disorder.
•Control participants will have no history of neurological or psychiatric illness and be taking no medications.

发起方

Professor Paul Fitzgerald