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Phase II Clinical trail on Chronic myelogenous leukemia (cancer of while blood cells) in children from 2 years to 18 years of age.

Phase 2
Completed
Conditions
Health Condition 1: null- Chronic Myelogenous Luekemia
Registration Number
CTRI/2011/08/001975
Lead Sponsor
BristolMyers Squibb India Pvt Ltd
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
110
Inclusion Criteria

Inclusion criterias:

1)Age 2 to 18 years.

2)Lansky or Karnofsky scale >50.

3)Life expectancy more than 12 weeks.

4)Any toxicity from recent therapies recovered to baseline or grade 1.

5)Adequate hepatic and renal function.

Exclusion Criteria

Prior therapy with dasatinib

Eligible for potentially curative therapy including hematopoietic stem-cell transplantation

Symptomatic central nervous system disease

Isolated extramedullary disease

Medical condition significantly impairing ability of patient to receive dasatinib

T315I mutation in BCR-AB

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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