Long-term Paired Associative Stimulation for Rehabilitation of Lower Extremities in Persons With Incomplete Tetraplegia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 5
- 试验地点
- 2
- 主要终点
- Daniels and Worthingham's Muscle Testing
研究概览
简要总结
The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles (1,2). In this study, the investigators will administer long-term paired associative stimulation to patients with incomplete cervical level SCI and investigate its effectiveness for lower extremity rehabilitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •cervical incomplete SCI
排除标准
- •metal inclusion in the head area
- •pacemaker
- •hearing device
- •high intracranial pressure
研究组 & 干预措施
PAS
The intervention is given to peripheral nerve - motor cortex pairs selected by the investigator.
干预措施: Paired associative stimulation (with eXimia magnetic stimulator and Dantec Keypoint® electroneuromyography device) (Device)
结局指标
主要结局
Daniels and Worthingham's Muscle Testing
时间窗: 1 month after the last stimulation session
leg muscles are evaluated on 0-5 scale
次要结局
未报告次要终点
研究者
Anastasia Shulga
Principal Investigator
Helsinki University Central Hospital