Effects of Commercially Available Probiotics on Hospital Outcome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 345
- 主要终点
- Reduction in Number of Days of Either Constipation or Diarrhea in Comparison to the Control Group
研究概览
简要总结
Probiotics have been shown to reduce the rate of diarrhea and constipation. The purpose of this study was to investigate if probiotics could improve outcome of hospitalized orthopedic elderly patients.
详细描述
The patients were divided into two groups. One received probiotics for 45 days and the second received placebo. The patients had a clinical and epidemiological as well as nutritional assessment. They were followed-up as for their bowel movements, abdominal pain and nosocomial infections and for the incidence of helicobacter pylori and clostridiume difficille diarrhea.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who were hospitalized in the Department of Geriatric Orthopedic Rehabilitation a week before their enrollment in the study and signed an informed consent.
排除标准
- •Known or suspected allergy to any probiotics
- •Neutropenia
- •Inability to sign an informed consent
结局指标
主要结局
Reduction in Number of Days of Either Constipation or Diarrhea in Comparison to the Control Group
时间窗: 45 days of measuring the outcome
Gastrointestinal motility was assessed by the number of days a patient was constipated or had diarrhea.
次要结局
- Improvement in Nutritional and Immunological Measurements(45 days)