Probiotics and Hospital Outcome in the Elderly
Not Applicable
Completed
- Conditions
- DiarrheaConstipation
- Registration Number
- NCT00794924
- Lead Sponsor
- Kaplan-Harzfeld Medical Center
- Brief Summary
Probiotics have been shown to reduce the rate of diarrhea and constipation. The purpose of this study was to investigate if probiotics could improve outcome of hospitalized orthopedic elderly patients.
- Detailed Description
The patients were divided into two groups. One received probiotics for 45 days and the second received placebo. The patients had a clinical and epidemiological as well as nutritional assessment. They were followed-up as for their bowel movements, abdominal pain and nosocomial infections and for the incidence of helicobacter pylori and clostridiume difficille diarrhea.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 345
Inclusion Criteria
- Patients who were hospitalized in the Department of Geriatric Orthopedic Rehabilitation a week before their enrollment in the study and signed an informed consent.
Exclusion Criteria
- Known or suspected allergy to any probiotics
- Neutropenia
- Inability to sign an informed consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Reduction in Number of Days of Either Constipation or Diarrhea in Comparison to the Control Group 45 days of measuring the outcome Gastrointestinal motility was assessed by the number of days a patient was constipated or had diarrhea.
- Secondary Outcome Measures
Name Time Method Improvement in Nutritional and Immunological Measurements 45 days