Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome

Not Applicable

Completed

• Conditions: Insulin Resistance; Polycystic Ovarian Syndrome
• Interventions: Device: whole body vibration; Device: Treadmill

• Registration Number: NCT05215223
• Lead Sponsor: Cairo University

Brief Summary

The purpose of this study is to investigate the effect of whole body vibration on insulin resistance in females with polycystic ovarian syndrome

Detailed Description

polycystic ovarian syndrome is a complex endocrine condition characterized by metabolic abnormalities such as insulin resistance, excess weight or obesity, diabetes, and an increased risk of cardiovascular disease.Despite previous studies reported that physical exercise improves insulin resistance in females with polycystic ovarian syndrome, there is no study yet investigate the effect of whole body vibration on insulin resistance

Study Timeline

• Study First Submitted: 2022-01-18
• Study First Submitted QC: 2022-01-18
• Study First Posted: 2022-01-31
• Study Start: 2022-03-30
• Status Verified: 2023-10
• Primary Completion: 2023-10-01
• Study Completion: 2023-10-10
• Last Update Submitted: 2023-10-14
• Last Update Posted: 2023-10-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 46

Inclusion Criteria

1. Females with polycystic ovarian syndrome.
2. Their ages will range from 20 to 35 years.

Exclusion Criteria

• 1-Smoking. 2-History of chronic disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
whole body vibration	whole body vibration	the patient will be received whole body vibration for three times/ week in addition to aerobic exercise for 3 times per week, 45 minutes per session for eight weeks
Aerboic exercise	Treadmill	Moderate intensity aerobic exercise in form of walking on treadmill for 3 times per week, 45 minutes per session for eight weeks
whole body vibration	Treadmill	the patient will be received whole body vibration for three times/ week in addition to aerobic exercise for 3 times per week, 45 minutes per session for eight weeks

Primary Outcome Measures

Name	Time	Method
Homeostasis Model Assessment (HOMA-IR)	eight weeks	Estimate insulin resistance (IR), it will be calculated according to the formula: fasting insulin (microU/L) x fasting glucose (nmol/L)/22.5.

Secondary Outcome Measures

Name	Time	Method
Waist circumference	eight weeks	by a tape measurement around the waist
waist hip ratio	eight weeks	The formula = waist circumference / hip circumference.
LH/FSH ratio	Eight weeks	To assess the severity of PCOS

Trial Locations

Locations (1)

Faculty of physical therapy; 🇪🇬 Giza, Egypt