Osteopathy and Latent Hypothyroidism

Not Applicable

• Conditions: Latent Hypothyroidism
• Interventions: Other: OMT

• Registration Number: NCT02430857
• Lead Sponsor: Emanuel Amier Diekmann

Brief Summary

This study evaluates the effectiveness of stimulating the neurological segments c8-th5 in patients with latent hypothyroidism.

One half of the participants will receive an osteopathic manuel treatment in order to stimulate the relevant segments, the other half will receive no treatment.

Detailed Description

Patients with latent hypothyroidism show an increased hormone status in TSH and a normal hormone status in fT4. A study has shown that osteopathic treatment had positive effects to some symptoms in patients with latent hypothyroidism. The study was using the pain inventory as the instrument to measure the effect. In this study we want to evaluate the effectiveness of the treatment on the hormone status (TSH, fT4) The intervention group will receive a neurological osteopathic stimulation over 5 weeks. A parallel control group will not receive any therapy.

A follow up blood screening (TSH, fT4) will be done. The results of both groups will be compared.

Study Timeline

• Study First Submitted: 2015-04-27
• Study First Submitted QC: 2015-04-27
• Study First Posted: 2015-04-30
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-17
• Last Update Posted: 2015-05-19
• Study Start: 2015-10
• Primary Completion: 2015-10
• Study Completion: 2016-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• latent hypothyroidism

Exclusion Criteria

• Factors that Alter Thyroxine and Triiodothyronine Binding in Serum
• Increased thyroxin-binding globulin
• Decreased thyroxin-binding globulin
• Binding inhibitors
• Inherited Salicylates
• Pregnancy
• Androgens
• Furosemide
• Neonatal state
• Anabolic steroids
• Free fatty acids
• Estrogens
• Glucocorticoids
• Phenytoin
• Hepatitis
• Severe illness
• Carbamazepine
• Porphyria
• Hepatic failure
• nonsteroidal antiinflammatory drug (variable, transient)
• Heroin
• Nephrosis
• Heparin
• Methadone
• Nicotinic acid
• Mitotane L-Asparaginase
• 5-Fluorouracil
• SERMS (e.g., tamoxifen, raloxifene)
• Perphenazine
• spinal pathologies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
OMT-Group	OMT	The OMT-group will get an osteopathic treatment once a week for 1 hour for 5 weeks. The blood will be screened again after the treatment.

Primary Outcome Measures

Name	Time	Method
Change in TSH Concentration	5 weeks