Bio-ADM as a Biomarker of Refilling in Chronic Hemodialysis Patient

• Conditions: Chronic Kidney Disease 5D
• Interventions: Biological: BioADM determination in plasma

• Registration Number: NCT05339009
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Aim of this study is to evaluate in a population of chronic kidney disease patients on dialysis (Stage 5D) the predictive value of bio-adrenomedullin (bio-ADM) level on vascular refilling rate.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-04
• Study Start: 2022-04-01
• Study First Submitted: 2022-04-13
• Study First Submitted QC: 2022-04-13
• Last Update Submitted: 2022-04-13
• Study First Posted: 2022-04-21
• Last Update Posted: 2022-04-21
• Primary Completion: 2022-12-31
• Study Completion: 2023-05-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
All patients receive conventional dialysis treatment at inclusion	BioADM determination in plasma	All patients receive conventional dialysis treatment at inclusion

Primary Outcome Measures

Name	Time	Method
Relationship between bio-ADM level and vascular refilling rate	Day 1	The refilling rate will be assessed by the ratio of relative blood volume and UF max

Secondary Outcome Measures

Name	Time	Method
Bio-ADM value according to comorbidity factors	Day 1	Bio-ADM value according to comorbidity factors (diabetes, heart failure and low-grade inflammation)

Trial Locations

Locations (1)

UH Montpellier; 🇫🇷 Montpellier, France