Randomised double-blind placebo controlled trial of treatment with pioglitazone in non-alcoholic steatohepatitis

Completed

• Conditions: Digestive System: Liver; Digestive System; Liver

• Registration Number: ISRCTN10319160
• Lead Sponsor: Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2003-09-12
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Added 27/03/08:
1. Age 18-70 years
2. Histological evidence of NASH

Exclusion Criteria

Added 27/03/08:
1. Alcohol consumption >21units in males and >14 units in females
2. Diabetes Mellitus
3. Consumption of drugs that cause fatty liver
4. Other liver diseases (clinical or on liver biopsy)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ecro-inflammation and fibrosis score on liver biopsy.

Secondary Outcome Measures

Name	Time	Method
1. Liver enzymes<br>2. Clinical and biochemical parameters of metabolic syndrome