The Quality of Life of Adult Survivors Who Received a Marrow Transplant as a Child
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Leukemia
- Sponsor
- Fred Hutchinson Cancer Center
- Enrollment
- 750
- Locations
- 1
- Primary Endpoint
- Neuroendocrine status of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
RATIONALE: Studying quality of life in cancer survivors may help determine the long-term effects of hematologic cancer and may help improve the quality of life for future cancer survivors.
PURPOSE: This clinical trial is studying the quality of life of adult cancer survivors who have undergone a previous bone marrow or peripheral stem cell transplant for a childhood hematologic cancer.
Detailed Description
OBJECTIVES: * Determine the extent to which adult cancer survivors who have undergone prior bone marrow or peripheral blood stem cell transplantation for a pediatric hematologic malignancy require ongoing health care and whether these needs change with increasing time after transplantation. * Correlate physical capabilities, body image, physical limitations, including sexuality issues which alter or influence lifestyle, with time after transplantation in these patients. * Determine whether cognitive abilities relative to memory and neurobehavioral ratings change with increasing time after transplantation in these patients. * Correlate social and relationship abilities with length of time after transplantation in these patients. OUTLINE: Patients and siblings complete a self-report quality of life questionnaire, including outcome assessments of neuroendocrine function, cognitive abilities, physical capability, and psychosocial behavior. PROJECTED ACCRUAL: Approximately 750 patients (375 adult cancer survivors \[case group\] and 375 siblings \[control group\]) will be accrued for this study within 7 years.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Neuroendocrine status of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
Cognitive capability of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
Physical capability of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
Psychosocial status of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18