Invisible funnel chest

Not Applicable

Completed

• Conditions: Circulatory System; Patients with cardiac symptoms and elevated Haller-Index in cardiac magnetic resonance imaging

• Registration Number: ISRCTN15355937
• Lead Sponsor: niversity Medical Centre Mannheim

Brief Summary

2023 Results article in https://doi.org/10.1038/s41598-023-38739-w (added 26/07/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-02-01
• Study Start: 2022-06-21
• Last Update Posted: 7 August 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

Patients who undergo cardiac magnetic resonance imaging for further evaluation of the heart due to cardiac symptoms (such as palpitations, dyspnea, atypical chest pain, syncope) and unobtrusive echocardiography, with relative thoracic constriction due to an elevated Haller-Index.

Exclusion Criteria

1. Inability to give informed consent
2. Definitive cardiac diagnosis

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of the Haller index, defined as the ratio of the transverse thoracic diameter divided by the frontodorsal diameter of the chest, by analyzing magnetic resonance imaging (MRI) data, measured at the time of study inclusion. For this, only two distances are measured on the MRI image and related to each other.

Secondary Outcome Measures

Name	Time	Method
1. Correction index, measured by cardiac magnetic resonance imaging (CMR) at the time of study inclusion. The correction index is defined as the minimum distance between the posterior sternum and anterior spine and the maximum distance between the anterior spine and most anterior portion of the chest. The difference between the two is divided by the latter (×100) to give the percentage of chest depth the defect represents. <br>2. Depression index, measured by CMR at the time of study inclusion. The depression index is derived from the absolute measurement of sternal depression using the transverse vertebral body diameter as a surrogate for height.<br>3. Intracardiac angles, measured by CMR at the time of study inclusion. Intracardiac angles were determined to describe the deviation of the heart axis by measuring three different intracardiac angles, including the angle between the perpendicular of the thorax and the apex of the right ventricular/insertion of the two ventricles/apex of the left ventricle.