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Pregnancy Outcomes Study

Not Applicable
Completed
Conditions
Health Condition 1: null- Determining the cause of deaths among preterm births (both live births and stillbirths)
Registration Number
CTRI/2018/03/012281
Lead Sponsor
Bill and Melinda Gates Foundation
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Pregnant women > 18 years of age

Women who are admitted likely to have a preterm delivery (20-37 weeks gestation) or women who have a known stillbirth (intrauterine fetal death >20 weeks).

Preterm infants who are admitted to the NICU at <7 days of age

Exclusion Criteria

Induced (medical) abortion

Unable to determine the gestational age at delivery

Gestational age < 20 weeks at delivery

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome of this study is cause of deaths in preterm births, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks, and in stillbirthsTimepoint: Enrollment to 28 days of neonatal age
Secondary Outcome Measures
NameTimeMethod
To determine the placental pathology associated with stillbirth and preterm deathsTimepoint: Enrollment to 28 days of life;To evaluate the rate of mortality by gestational age and birth weightTimepoint: Enrollment to 7 days of life;Interventions associated with reduced risk of mortality among preterm births or stillbirthTimepoint: Enrollment to 28 days of life;Obstetric risk factors for stillbirth and neonatal mortalityTimepoint: Enrollment to delivery;To determine causes among extremely preterm (28 weeks) very preterm (28-32 weeks) preterm (32-37 weeks) in relation to the cause of deathTimepoint: Enrollment to 28 days of life;To determine the pathogens associated with stillbirth and preterm deathsTimepoint: Enrollment to 28 days of neonatal age
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