Validation of The Telephone Interview for Cognitive Status and Montreal Cognitive Assessment against neuropsychological assessment for postoperative cognitive dysfunction in the elderly (The TINMAN study).

Completed

• Conditions: memory loss after surgery; Postoperative Cognitive Disorder; 10009841

• Registration Number: NL-OMON48512
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-08-01
• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 105

Inclusion Criteria

In order to be eligible to participate in this study, a patient must meet all
of the following criteria:
- Elective minor, moderate or major surgery, according to the definition of the
European Society of Anesthesiology
- Age *65 years
- ASA l - lV
- Fluent in written and spoken Dutch
- Willing and able to undergo neuropsychological assessment, and have the MoCA
and TICS administered both pre- and approximately one month postoperatively.

Exclusion Criteria

- Emergency surgery
- Previously diagnosed cognitive dysfunction
- Patients who are unable to understand or fill-in questionnaires in Dutch

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Agreement between performance on the TICS, MoCA and NPA and its cognitive<br /><br>domains<br /><br>o The correlation between the TICS, MoCA and total NPA score and baseline<br /><br>characteristics<br /><br>o The correlation between the TICS, MoCA and the cognitive domain scores of the<br /><br>NPA and baseline characteristics<br /><br>o The correlation between TICS and MoCA total scores and cognitive domain<br /><br>scores pre- and approximately one month postoperatively</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- The validity, sensitivity and specificity of the TICS and MoCA questionnaires<br /><br>compared to the gold standard (NPA) both on baseline and on postoperative<br /><br>change scores from baseline</p><br>