NCT05377216招募中早期 1 期
Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation
适应症
干预措施
相关药物
试验速览
- 阶段
- 早期 1 期
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Ventricular Effective Refractory Period
研究概览
简要总结
Prospective cohort study evaluating the electrophysiologic and biochemical effects of stellate ganglion block in patients with ventricular tachycardia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Planned catheter based VT ablation
- •Age at least 18 years
排除标准
- •Pregnancy
- •Contraindication to SGB or VT ablation
- •Hypersensitivity of local anesthetic of amide type
- •Hemodynamic instability during the procedure prior to the study protocol
研究组 & 干预措施
Stellate ganglion block
Experimental
All subjects will undergo stellate ganglion block during their VT ablation procedure
干预措施: Stellate Ganglion Block (Drug)
结局指标
主要结局
Ventricular Effective Refractory Period
时间窗: 30 minutes following stellate ganglion block
Change in Ventricular Effective Refractory Period at 600ms drive train (measured in milliseconds)
次要结局
- Neuropeptide Y(30 minutes following stellate ganglion block)
- Ventricular Arrhythmia Inducibility(30 minutes following stellate ganglion block)
研究者
研究点 (1)
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