A Trial Comparing Bowel Preparation and Patient Tolerability of Miralax Versus Golytely
- Conditions
- Colonoscopy
- Interventions
- Registration Number
- NCT00889655
- Lead Sponsor
- Oregon Health and Science University
- Brief Summary
Prior to colonoscopies, the colon is cleansed using a laxative. Golytely is approved by the FDA for this purpose. Another laxative, called MiraLax, is approved by the FDA to relieve constipation, but it is not approved specifically for preparation for a colonoscopy. Nonetheless, it is commonly used in clinical practice for this purpose, just as is Golytely. The purpose of this study is to compare Golytely and MiraLax in two ways: to see whether one is better tolerated by patients than the other and to see whether one more effectively cleanses the bowel than the other. The investigators' hypothesis is that these 2 bowel preparation methods are equally effective in bowel cleansing, but that patients prefer Miralax to Golytely.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 432
- average risk screening for colon cancer
- subjects with a history of constipation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description MiraLax MiraLax (polyethylene glycol 3350) 216 patients will be randomized to take 238 gm of miralax mixed with 64 oz of gatorade for their bowel cleanser Golytely Golytely (polyethylene glycol) 216 patients at random will provided a prescription for the standard 4 L golytely preparation as the bowel cleanser for their colonoscopy
- Primary Outcome Measures
Name Time Method bowel cleanliness as rated by the boston bowel prep survey measured at the time of colonoscopy
- Secondary Outcome Measures
Name Time Method patient tolerability measured at check in to colonoscopy
Trial Locations
- Locations (1)
Oregon Health & Sciences University
🇺🇸Portland, Oregon, United States