Comparative Study on the Effectiveness of Gandhakadi Yoga and Disodium Hydrogen Citrate in Treating urinary tract infection

Phase 2/3

Not yet recruiting

• Conditions: Urinary tract infection, site notspecified. Ayurveda Condition: MUTRAKRUCCRAM,

• Registration Number: CTRI/2025/05/087829
• Lead Sponsor: Department of Shalyatantra Samanya Shree Saptashrungi Ayurved Mahavidyalaya

Brief Summary

Urinary Tract Infection (UTI), commonly presenting with symptoms like painful urination, frequency, and burning sensation, is often correlated with Mutrakruccha in Ayurveda. Conventional treatment includes antibiotics and urinary alkalizers such as disodium hydrogen citrate, which may lead to side effects or antibiotic resistance with repeated use. Ayurveda offers various formulations for managing Mutrakruccha, including Gandhakadi Yoga, which possesses antimicrobial, anti-inflammatory, and diuretic properties.

This randomized controlled clinical trial aims to evaluate the efficacy and safety of Gandhakadi Yoga in the management of Mutrakruccha, in comparison with disodium hydrogen citrate. The study will assess symptomatic relief, improvement in urine analysis parameters, and recurrence rate over a defined treatment period.

The sample size of this study will be 60 .

The outcome of this study may support the integration of Ayurvedic formulations in UTI management, offering a natural and holistic alternative with potentially fewer side effects.

Therefore the drug used in this trial can have an effective result in UTI

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-06-14
• Study Start: 2025-10-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Clinical diagnosis of UTI-associated Mutrakruccha.

Exclusion Criteria

• 1)Pregnant or lactating women 2) Patients with known allergies or Contraindications to the study medications 3) Patients with severe renal impairment or Other serious comorbidities.
• 4. Patients having malignancy of any part of urinary tract.
• 5. Patients having sulphur allergy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To study the efficacy of Gandhakadi Yoga in Mutrakruchhra with Special	1 year
reference to Urinary tract infection.	1 year
Urinary tract infection will be studied	1 year
Effect of gandhakadi yoga will be studied on given sample size	1 year

Secondary Outcome Measures

Name	Time	Method
To study the efficacy of Gandhakadi Yoga on comparison with disodium	hydrogen citrate in Mutrakruchhra with Special reference to Urinary tract

Trial Locations

Locations (1)

Department Of Shalyatanta,Shree Saptashrungi Ayurved Mahavidyalaya And Hospital; 🇮🇳 Nashik, MAHARASHTRA, India

Department Of Shalyatanta,Shree Saptashrungi Ayurved Mahavidyalaya And Hospital

🇮🇳Nashik, MAHARASHTRA, India

DrPayal Ashish Kela

Principal investigator

9284443710

payalkela405@gmail.com