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A deep learning model for glaucoma diagnosis based on optical coherence tomography (OCT) : a multicenter study

Conditions
OCT data of glaucoma patients and normal population for developing deep learning model
glaucoma
deep learning model
optical coherence tomography
Registration Number
TCTR20230227003
Lead Sponsor
Faculty of Medicine Siriraj Hospital, Mahidol University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
500
Inclusion Criteria

1. Patients with age over 18 years old
2. Patients who diagnosed glaucoma 400 eyes
3. Normal subject without glaucoma 100 eyes
4. Each subject should have OCT result and HVF 24-2 result within the same period (not more than 6 months apart)

Exclusion Criteria

1. Patients with ocular comorbidities which obscure OCT data gathering
2. OCT signal strength less than 6
3. Patient with other comorbidities which interfere HVF 24-2 result e.g. retinal disease or neuro-ophthalmologic disease
4. Unreliable HVF result (fixation loss > 20%, false positive > 20%, false negative > 20%, rim artifact, lid effect, clover leaf)

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
efficacy of the model end of study AUC, true positive, true negative, sensitivity, specificity
Secondary Outcome Measures
NameTimeMethod
correlation between predicted outcome from the model based on OCT versus HVF 24-2 result end of study comparison of visual field index (VFI) using independent sample T-Test
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