Study of Cerebral Compliance in Neurosurgical Intensive Care Units (EC2)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 7
- 主要终点
- Intracranial pressure (mmHg)
研究概览
简要总结
Despite the massive use of intracranial pressure in neuro-resuscitation, there is still no cerebral compliance evaluation index used in current practice to guide therapy.
In treatment guidelines for intracranial hypertension, patients are placed in a prone position at about 30 degrees. Several times a day, during nursing care, patients are flattened, which corresponds to a cerebral compliance test by adding a volume of cerebrospinal fluid to the cranial box.
详细描述
This study aims to analyse the shape of the different components of the intracranial pressure waves (P1, P2, and P3) when the patient is flattened to determine an index to define the level of cerebral compliance.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Continuous intracranial pressure monitoring
- •Sedated patient on mechanical ventilation
排除标准
- •Craniectomy
- •Major hemodynamic failure
结局指标
主要结局
Intracranial pressure (mmHg)
时间窗: Year : 1
Intracranial pressure is measured before (Raising the head by 30°) and during the flattening (Raising the head by 0°). Theses measures are done twice a day. The mean of theses values is calculated.
次要结局
- Correlation between ICP (Intra Cranial Pressure) doses and cerebral compliance(Year : 1)