Role of Low Carbohydrate Nutrient in Healing of Infected Diabetic Foot

Completed

• Conditions: Carbohydrate Ingestion

• Registration Number: NCT06759688
• Lead Sponsor: Sarah Magdy Abdelmohsen

Brief Summary

A low-carbohydrate diet, when combined with standard wound care and diabetes management, appears to accelerate the healing of infected diabetic foot, improve blood glucose control, reduce systemic inflammation and promoting overall patient recovery. This approach could be considered a beneficial adjunct therapy in the treatment of diabetic foot infections.

Detailed Description

The research was a case control study. It conducted prospectively from January 2019 to December 2023 in the surgery department of Aswan university hospital. It involving patients with diabetic foot infections. The patients were divided into two groups of patients. The first group committed to not eating carbohydrates in food. The second group ate their daily routine and did not adhere to the carbohydrate's restriction. The diabetic food infection classified from mild, moderate and sever, as per the Infectious Diseases Society of America (IDSA) Infection Severity Classification.

Study Timeline

• Study Start: 2019-01-01
• Primary Completion: 2023-12-30
• Study Completion: 2023-12-30
• Study First Submitted: 2024-12-30
• Study First Submitted QC: 2024-12-30
• Status Verified: 2025-01
• Study First Posted: 2025-01-06
• Last Update Submitted: 2025-01-06
• Last Update Posted: 2025-01-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Patients complained of diabetic foot infections graded 0 to 4 with absent signs of ischemia.

Exclusion Criteria

Patients with foot gangrene grade 5 The presence of foot ischemia Those who refused to participate

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in the wound size and healing	3-6 months	Wound healing rate (%) = \[ (Initial wound size - Wound size after 1 week) / (Initial wound size)\] × 100

Trial Locations

Locations (1)

Aswan University Hospital; 🇪🇬 Aswan, Egypt