NCT00811980已完成不适用
The Effects of Linezolid and Vancomycin on Inflammation and Cellular Signaling Vents
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- IL-6
研究概览
简要总结
We will determine if linezolid inhibits cellular activation and production of pro-inflammatory cytokines, providing mechanistic rationale for its clinical efficacy and the justification for further investigations in S. Aureus sepsis.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy, taking no medications, and not recently hospitalized
排除标准
- •Infection (active)
研究组 & 干预措施
Heathy Subjects
干预措施: Linezolid or Vancomycin (Drug)
结局指标
主要结局
IL-6
时间窗: 12 Months
Measurement of IL-6 release in response to MRSA.
次要结局
- MCP-1(12 Months)
研究者
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