NCT01906411
Completed
Not Applicable
Dopaminergic Function and Food Reward
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Adiposity
- Sponsor
- University Hospital Tuebingen
- Enrollment
- 36
- Locations
- 1
- Primary Endpoint
- Differential brain functions in the dopaminergic reward system
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The broad aim of the study is to obtain a better understanding of alterations in mesolimbic reward pathways in adiposity based on the hypothesis of a hypofunctioning reward system in obesity.
This will be achieved by integrating a functional neuroimaging (fMRI) with behavioral reward tasks and the modulation of the dopamine level by dopamine depletion.
Investigators
Sabine Frank
Dr.
University Hospital Tuebingen
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •fMRI contraindications
- •claustrophobia
Outcomes
Primary Outcomes
Differential brain functions in the dopaminergic reward system
Time Frame: 4 hours after intake of the dopamine depletion or balanced aminoacid drink
differential brain fuctions will be measured by blood oxygen level dependent effect.
Secondary Outcomes
- amino acid level changes due to dopamine depletion(4 hours after intake of the dopamine depletion or balanced aminoacid drink)
Study Sites (1)
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