IRCT20181109041596N1招募中3 期
Evaluation of effect of fluoxetine on the clinical prognosis in patients with anterior ischemic optic neuropathy (AION) according to evaluations of visual acuity and VEP tests as main outcomes, in comparison between drug and placebo groups.
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Iranian patients
- •Age over 18 years old
- •Patients with diagnosis of AION; non-arteritic type
排除标准
- •Pregnancy before or during study
- •Past medical history of cataract, glaucoma ( open or close angle ) congenital eye disease such as cloboma and involvement with disease effecting the central visual field of patient
- •Patients with past medication history of using fluoxetine or other psychological medications including antidepressants
- •Patients suffering from psychological disease
- •Patients who use medications including :arthemeter? astemizol, cisapride, eliglustat, goserelin, isocarboxazide, artemether, leuprolide, linezolid, lumefantrine, methylene blue, phenelzine, pimozide, procarbazine, selegiline, thioridazine, tranylcypromine
- •Patients diagnosed with immunologic and collagen vascular disease
- •Patients with symptoms of or diagnosed with giant cell arteritis and positive CRP more than 3+ or ESR more than 40
- •Trauma or surgery history of eyes
- •Duration between involvement and interview more than 3 weeks
- •Patients without compliance of using fluoxetine or disagrement of patient to continue accompanying the study
- •Involvement by glaucoma
- •Involvement by cataract
- •Change in depression questionnaire score lower than 1 score in comparison to first and forth visit ( means the poor compliance of patient that has not used fluoxetine
- •Death of patient
研究者
相似试验
已完成
不适用
Effect of fluoxetine on clinical symptoms and echocardiographic findings in patients with mitral valve prolapse and generalized anxiety disorder.Condition 1: Generalized anxiety disorder. Condition 2: mitral valve prolapse.Generalized anxiety disorderMitral (valve) prolapseIRCT2014102819721N1Sabzevar University of Medical Science60
已完成
3 期
Evaluation of effect of fluoxetine on the clinical prognosis in patients with Optic neuritisOptic neuritisIRCT20200719048138N1Iran University of Medical Sciences100
尚未招募
不适用
The effectiveness of fluoxetine in the treatment of depressioMajor Depression.Mood disorder due to known physiological condition with major depressive-like episodeF06.32IRCT20220706055386N1Esfahan University of Medical Sciences40
已完成
2 期
Evaluating the effect of Fluoxetine on symptoms and quality of life of patients with moderate to severe irritable bowel syndrome in adults.Irritable bowel syndrome.Irritable bowel syndromeIRCT138805012159N2Isfahan University of Medical Sciences180
已完成
不适用
The effect of Fluoxetine and Cognitive- Behavior Therapy on sexual functioIRCT2013091014619N1Vice chancellor for research, Kashan University of Medical Sciences58