IRCT20181109041596N1
Recruiting
Phase 3
Evaluation of effect of fluoxetine on the clinical prognosis in patients with anterior ischemic optic neuropathy (AION) according to evaluations of visual acuity and VEP tests as main outcomes, in comparison between drug and placebo groups.
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Iran University of Medical Sciences
- Enrollment
- 100
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Iranian patients
- •Age over 18 years old
- •Patients with diagnosis of AION; non\-arteritic type
Exclusion Criteria
- •Pregnancy before or during study
- •Past medical history of cataract, glaucoma ( open or close angle ) congenital eye disease such as cloboma and involvement with disease effecting the central visual field of patient
- •Patients with past medication history of using fluoxetine or other psychological medications including antidepressants
- •Patients suffering from psychological disease
- •Patients who use medications including :arthemeter? astemizol, cisapride, eliglustat, goserelin, isocarboxazide, artemether, leuprolide, linezolid, lumefantrine, methylene blue, phenelzine, pimozide, procarbazine, selegiline, thioridazine, tranylcypromine
- •Patients diagnosed with immunologic and collagen vascular disease
- •Patients with symptoms of or diagnosed with giant cell arteritis and positive CRP more than 3\+ or ESR more than 40
- •Trauma or surgery history of eyes
- •Duration between involvement and interview more than 3 weeks
- •Patients without compliance of using fluoxetine or disagrement of patient to continue accompanying the study
Outcomes
Primary Outcomes
Not specified
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