This study investigates the relevance of male age and male factors impacting on the chance of live births from in vitro fertilization treatment cycles
Active, not recruiting
- Conditions
- Infertility treated by in vitro fertilisationReproductive Health and Childbirth - Fertility including in vitro fertilisation
- Registration Number
- ACTRN12618001820291
- Lead Sponsor
- PIVET medical centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 1280
Inclusion Criteria
all first fresh autologous cycles in heterozygous couples undergoing IVF with single embryo transfer.
Female ages ranged 22 years to 48 years
Male ages ranged 23 years to 64 years
Exclusion Criteria
donor cycles using donor gametes
frozen cycles
natural cycles
assessment cycles and other types of fertility treatments such as IUI
azoospermic males
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method clinical pregnancy defined as elevated serum ßhCG and vaginal ultrasound showing intra-uterine gestational sac.[35 days after oocyte pick-up];Live birth – data-linkage to medical records in clinic database compiled from patient information and hospital records by a single coordinating nurse, who contacts each patient within 7 days of their expected due date[>18 weeks after oocyte pick-up ( by convention this means gestation >20 weeks).]
- Secondary Outcome Measures
Name Time Method sperm concentration (total number of spermatozoa /ml<br>[within 3 months before start of IVF cycle];sperm motility (WHO progressive motility A and B grades) /ml<br>[within 3 months before start of IVF cycle];sperm morphology (WHO strict criteria) /ml<br>[within 3 months before start of IVF cycle];DNA fragmentation index (Halo test) % failing to display halo[within 3 months before start of IVF cycle]