Attentional effects on the processing of noxious brief electric stimuli measured with EEG - Event-Related Potential (ERPs) testing.
- Conditions
- somato-sensore informatie verwerkingcognitive functioningnociception
- Registration Number
- NL-OMON30353
- Lead Sponsor
- Katholieke Universiteit Nijmegen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 32
Inclusion Criteria
Between 18-60 years of age.
Exclusion Criteria
Neurologic / psychiatric history
Use of psychoactive substances
Visual/auditory impairment
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main parameters will be ERP component amplitudes (in µV) and VAS values (on<br /><br>a continuous scale between 0-10). ERP component amplitudes from both visual<br /><br>warning stimuli (N1, P2, N2 and P3, as well as CNV) and noxious stimuli (N140,<br /><br>P260) will be determined. In a previous pilot experiment with healthy<br /><br>volunteers (CMO-nr.: 2005/288) we found marked effects on noxious stimulus<br /><br>predictability on both the CNV preceding the noxious stimuli and the P260<br /><br>following the noxious stimuli.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Behavioral responses to the attentional task<br /><br>1. Omissions and Error rates<br /><br>2. Reaction Times<br /><br><br /><br>Test scores to the Thayer scales<br /><br>ECG: heart rate and heart rate variability<br /><br>demographic data</p><br>