“A comparative study of Ultrasound guided Supraclavicular brachial plexus block using Bupivacaine alone and the combination of Bupivacaine and Buprenorphine in patients undergoing elective upper limb orthopaedic surgeries. â€
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Onset of action is faster and duration of action is prolonged when Combination of Bupivacaine and Buprenorphine is used compared to Bupivacaine alone
研究概览
简要总结
For ultrasound guided supraclavicular brachial plexus block, one group
received bupivacaine alone anad other group received bupivacaine and
buprenorphine. On comparing the two groups, it was found out that,
Onset of sensory blockade was similar in both the groups.
Onset of motor blockade was found to be earlier in bupivacaine alone
group.
Duration of analgesia was significantly prolonged in group that
received buprenorphine compared to bupivacaine alone.
The need for rescue analgesic is significantly delayed in the group that
received buprenorphine compared to bupivacaine alone.
There was no significant difference in the hemodynamic parameters in
both the groups.
There was no opioid related side effects in both the groups.
No other complications were seen in both the groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Assessed patients of ASA I and II status.
- •Both gender.
- •Normal biochemical and hematological parameters.
- •Age group between 20 -60years
- •Patients weighing 50-70 Kgs.
- •Mallampati score of I and II
- •No known neurological deficit
- •No local sepsis.
排除标准
- •Patients who have not given consent.
- •Patients with anticipated difficult airway.
- •Neurological disorders
- •History of cardiovascular and respiratory disorders
- •Local bony deformities
- •History of bleeding disorders
- •Extremely obese patients.
结局指标
主要结局
Onset of action is faster and duration of action is prolonged when Combination of Bupivacaine and Buprenorphine is used compared to Bupivacaine alone
时间窗: 6 to 7 hours
次要结局
- Post operative analgesia is prolonged when combination of Bupivacaine and Buprenorphine are used(2to 3 hours)
研究者
ZOHRA FATIMA
Gulbarga institute of medical sciences